SPASTICITY

The utility of soleus H-reflex for monitoring and troubleshooting intrathecal baclofen administration

  • Objective: Determine how serial recordings of soleus H-reflex can help determine adequate or inadequate delivery of intrathecal baclofen for control of spasticity
  • Lead Investigator: Dobrivoje S. Stokic, M.D., D.Sc.
  • Outside Collaborator: Stuart A. Yablon, M.D., Glenrose Rehabilitation Hospital and Department of PMR, University of Alberta, Edmonton, Canada
  • Related Publications: 
  • Funding: Medtronic Inc. Minneapolis, MN, The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting internally (not open to public)

Complications of the implantable drug delivery system for intrathecal administration of baclofen for control of spasticity after acquired brain injury

  • Objective: Determine prevalence and types of system malfunctions among the recipients of intrathecal baclofen pump for control of spasticity
  • Co-Principal Investigators: Dobrivoje S. Stokic, M.D., D.Sc. and Stuart A. Yablon, M.D., Glenrose Rehabilitation Hospital and Department of PMR, University of Alberta, Edmonton, Canada
  • Outside Collaborators: Markus Kofler, MD, Department of Neurology, Hochzirl Hospital, Zirl, Austria; Ivana Stetkarova, MD, Department of Neurology, 3rd Medical Faculty, Charles University, Prague, Czech Republic
  • Related Publications: 
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

Characteristics of gait in patients with moderate-to-severe muscle hypertonia after acquired brain injury

  • Objective: To describe changes in gait parameters and muscle activation patterns in patients with moderate-to-severe hypertonia after acquired brain injury
  • Lead Investigator: John W. Chow, Ph.D.
  • Outside Collaborator: Stuart A. Yablon, M.D., Glenrose Rehabilitation Hospital and Department of PMR, University of Alberta, Edmonton, Canada
  • Related Publications: 
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

Effect of intrathecal baclofen on gait in patients with muscle hypertonia after acquired brain injury

  • Objective: Describe changes in gait and muscle activation patterns after bolus or continuous intrathecal baclofen administration for control of spasticity after acquired brain injury
  • Lead Investigator: John W. Chow, Ph.D.
  • Outside Collaborator: Stuart A. Yablon, M.D., Glenrose Rehabilitation Hospital and Department of PMR, University of Alberta, Edmonton, Canada
  • Related Publications: 
  • Funding: Medtronic Inc. Minneapolis, MN, The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting internally (not open to public)

Impact of spasticity on daily activity in multiple sclerosis (collaborative study)

  • Objective: Describe subjective impression of how spasticity affects various aspects of physical and psycho-social health in person with multiple sclerosis
  • MRC Investigator: Dobrivoje S. Stokic, M.D., D.Sc.
  • Study Site Lead Investigator: Ljubica Konstantinovic, M.D., D.Sc., Clinic for Rehabilitation “Dr. M. Zotovic”, Department of PMR, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Related Publications: New
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting at the collaborative study site